Test Overview:

Tests for both variants associated with Piebald. These alleles are associated with Piebald, Parti, Landseer or Random White Spotting among several breeds where these patterns are observed. The inheritance and expression can vary depending on the breed. Please note that it has also been shown that sp/sp does not present as piebald in many wolves and nordic dog breeds.


Trait (Associated with Phenotype)


MITF-M on Chromosome 20

Variant Detected:

g.chr20:21836563insSINE Length polymorphism (repeat CAGA) chr20:21839332-21839366 MITF-M


It is a trait and so is tested based on preference, not usually for health concerns.

Mode of Inheritance:

Autosomal Recessive with Incomplete Penetrance

Research Citation(s):

Korberg et al. PLoS One, A Simple Repeat Polymorphism in the MITF-M Promoter Is a Key Regulator of White Spotting in Dogs 9;8, e104363.
Schmutz S, TG Berryere and DL Dreger. MITF and white spotting in dogs: a population study. Journal of Heredity 2009, 100(Supl 1):S66-S74.)

Associated Breed(s):

American Bulldog , American Bully , American Cocker Spaniel, American Eskimo Dog, American Foxhound, American Hairless (Rat) Terrier, American Pit Bull Terrier, American Staffordshire Terrier, Anatolian Shepherd, Asian Shepherd, Aussiedoodle, Australasian Bosdog, Australian Bulldog, Australian Cattle Dog, Australian Cobberdog, Australian Labradoodle , Australian Shepherd, Australian Stumpy Tail Cattle Dog, Basenji, Basset Hound, Beaglier, Belgian Malinois Shepherd, Bernedoodle, Bichon Frise, Biewer Terrier, Bloodhound, Boerboel, Border Collie, Bordoodle, Borzoi, Boston Bulldog, Boston Terrier, Boxer , Boykin Spaniel, Bracco Italiano, Brazilian Terrier, Briard, British Bulldog, Brittany Spaniel , Bull Arab, Bull Terrier, Bullmastiff, Canaan Dog, Cane Corso Italiano, Cardigan Welsh Corgi, Catahoula, Catahoula Leopard Dog, Caucasian Shepherd Dog, Cavador, Cavalier King Charles Spaniel, Cavoodle, Cesky Terrier, Chesapeake Bay Retriever , Chihuahua, Chinese Crested, Chow Chow, Clumber Spaniel , Cockapoo, Cocker Spaniel, Collie Rough, Collie Smooth, Colonial Cocker Spaniel, Coonhound, Dachshund , Dachshund Short Hair, Dachshund Standard Long Hair, Dachshund Standard Smooth Hair, Dachshund Standard Wire Hair, Dachshund Wire Hair, Dalmatian, Dandie Dinmont Terrier, Dobermann, Dogo Argentino, Dogue de Bordeaux, Double Doodle, Dutch Shepherd, Dwarf Poodle, English Springer Spaniel, English Toy Spaniel , English Toy Terrier, Estrela Mountain Dog, Field Spaniel, Finnish Lapphund, Flat Coated Retriever, Fox Terrier (Toy), Foxhound , French Bulldog, German Shepherd Dog, German Shorthaired Pointer, German Wirehaired Pointer, Giant Schnauzer, Glen of Imaal Terrier, Goldendoodle, Grand Basset Griffon Vendeen, Great Dane, Great Pyrenees, Greater Swiss Mountain Dog, Greyhound , Groodle, Harlequin Pinscher, Havanese, Havanese Terrier Toy, Huntaway, Ibizan Hound, Icelandic Sheepdog, Irish Terrier, Irish Water Spaniel, Italian Greyhound, Italian Spinone, Jack Russell Terrier, Japanese Spitz, Kaninchen Dachshund, Keeshond, Koolie , Kromfohrländer, Labradoodle , Labradoodle Retrodoodle , Lakeland Terrier , Lancashire Heeler, Landseer ECT, Lapponian Herder, Large Munsterlander, Leonberger, Lhasa Apso, Lowchen, Maltese, Maltese Shih tzu, Maremma Sheepdog, Mastiff , Miki, Miniature American Shepherd, Miniature Australian Bulldog, Miniature Australian Shepherd, Miniature Bull Terrier, Miniature Dachshund, Miniature Dachshund Long Hair, Miniature Dachshund Short Hair, Miniature Dachshund Smooth Hair, Miniature Dachshund Wire Hair, Miniature Fox Terrier, Miniature Pinscher , Miniature Poodle, Miniature Schnauzer, Miniature Yorkshire Terrier, Moodle, Mountain Dog , Moyen Poodle, Munsterlander, Murray River Retriever, Neapolitan Mastiff, New Zealand Heading Dog, Newfoundland, Norfolk Terrier , Norwegian Elkhound, Norwich Terrier, Nova Scotia Duck Tolling Retriever , Old English Mastiff , Old English Sheepdog , Otterhound, Parson Russell Terrier, Pembroke Welsh Corgi, Peruvian Hairless Dog, Petit Basset Griffon Vendeen, Pharaoh Hound, Plott Hound, Pointer, Polish Lowland Sheepdog, Pomeranian, Porti-Doodle, Portuguese Podengo, Portuguese Water Dog, Prague Ratter, Presa de Canario, Puli, Pumi, Pyrenean Sheepdog, Rat Terrier, Red and White Setter, Russian Toy, Saluki, Samoyed, Sarplaninac, Schapendoes, Schnoodle, Scottish Deerhound, Scottish Terrier , Sealydale Terrier, Sealyham Terrier , Shar Pei, Sheepadoodle, Shetland Sheepdog, Shih tzu, Short Bully, Shortybull, Siberian Husky, Silky Terrier , Skye Terrier, Sloughi, Smithfield, Smooth Fox Terrier, Southern Cross Bulldog, Spanatriever, Spanish Water Dog, Spoodle, Springador, Staffordshire Bull Terrier , Standard Poodle, Standard Schnauzer, Sussex Spaniel, Swedish Lapphund, Swedish Vallhund, Tenterfield Terrier , Tibelier, Tibetan Mastiff, Tibetan Spaniel, Tibetan Terrier , Toy Poodle, Water Spaniel , Welsh Springer Spaniel, Welsh Terrier , West Highland White Terrier , Whippet , White Swiss Shepherd, Wire Fox Terrier, Xoloitzcuintle (Mexican Hairless), Yakutian Laika, Yorkshire Terrier,