Dog ichthyosis a hereditary, monogenic, cornification disorder, appearing early and persisting for life. Cornification disorders form a heterogeneous group of diseases characterised by abnormal differentiation (cornification) of the epidermis. Signs associated with ichthyosis can start from a very young age in some breeds, with hairless skin on the underside becoming reddened and then developing a brown scale and a wrinkly appearance.  By the time the dog reaches adulthood the underside of the dog is covered in brown scale, with white-to-tan scales visible in haired areas.  The feet may occasionally be affected with thickening and cracking of the footpads. Treatment of ichthyosis is aimed at relieving dryness and scale with keratolytic shampoos, which may need to be used from weekly to daily.  Moisturising oils are usually applied as well, and these help to maintain the barrier function of the skin and prevent secondary infections.  Diet is supplemented with fatty acids, and sometimes retinoids may also be used.  Infections are treated appropriately.  There is no cure, and affected animals should not be used for breeding.