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K Locus (Dominant Black)

Description

The KB variant of the CBD103 gene promotes eumelanin (black pigment) synthesis by blocking the agouti gene expression at the A Locus (which would otherwise inhibit MC1R production of eumelanin). 
The alternate ky variant of the CBD103 gene disrupts the normal function of the CBD103 gene allowing for agouti (A locus) gene expression and the inhibition of black pigment synthesis. 
Therefore, because KB is dominant, only one copy of KB is required to inhibit agouti gene expression.
Want to understand more about the K Locus? Click here for a Fact Sheet.

Recommended Breeding

Traits

K Locus (Dominant Black)

$ 50.00

1

Associated Breed(s):

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Labels:

Currently Undefined

A label cannot be assigned at this time as this is outside the defined scope

Category:

Trait (Associated with Phenotype)

Severity:

It is a trait and so is tested based on preference, not usually for health concerns.

Gene:

CBD103

Variant Detected:

chr16:58965448-58965450 (canFam3): 3 bp deletion (del GGA)

Mode of Inheritance:

Autosomal Dominant

OMIA Reference:

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Fact Sheet:

Click to View Fact Sheet