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Laryngeal Paralysis (St Bernard/Leonberger Type)

Description

Laryngeal Paralysis affects dogs and is an inherited neurological disease.

Affected dogs typically present with difficulty breathing, often described as loud and harsh, difficulty swallowing, and changes in the dog’s vocalisations clinical signs, at less than 5 years of age.

In severe cases, a dog’s mobility may be affected by an uncoordinated gate, stumbling and tripping, exercise intolerance and muscle deterioration.

In some dogs, this condition may be managed with conservative measures such as changes in lifestyle while others require surgical treatment to reduce severe respiratory signs.

This condition may result in emergent respiratory distress or aspiration pneumonia which can be fatal.

Recommended Breeding

Diseases

Laryngeal Paralysis (St Bernard/Leonberger Type)

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Associated Breed(s):

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Labels:

Category:

Nervous system / Neurologic - Associated with the brain, spinal cord and nerves

Severity:

Moderate. This disease can cause significant signs of discomfort and/or dysfunction in affected animals. It may involve relatively high treatment/management costs, and can sometimes reduce life expectancy.

Gene:

CNTNAP1

Variant Detected:

chr9:20172413 (canFam4): C/T

Mode of Inheritance:

Autosomal Recessive

OMIA Reference:

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