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M Locus (Merle/Dapple)

Description

Orivet, a leader in innovative animal health, provides over 260 Tests for Dog Breeders.

Merle, dapple the M Locus coat colour test to determines the allele size of the mutation. Our test can detect the various patterns M (classic Merle), Mc (cryptic), Ma (atypical) Mh (harlequin) and m (non-merle). These various types allow you determine the effect on coat colour and health status. Please see more in Test Overview below.

Please Note: Orivet results are on average 2 to 3 base pairs lower than reported previously (Langevin et al; 2018). This may result in some Merle classification differences between laboratories.
Orivet has a sublicense granted by IDEXX Laboratories Inc. In some cases you may need to include a hair sample with ALL swab samples submitted. Click here to download our Merle Hair Sample Submission Form.
Click here for a Merle Fact Sheet.

Recommended Breeding

Traits

M Locus (Merle/Dapple)

$ 50.00

Associated Breed(s):

Click here to view Associated Breeds

Labels:

Pathogenic (P)

A healthcare provider can use molecular testing information in clinical decision‑making for breeding programs and/or screening.

Category:

Trait (Associated with Phenotype)

Severity:

It is a trait and so is tested based on preference, not usually for health concerns.

Gene:

SILV

Variant Detected:

250 base pair SINE insertion, oligo(dA)-rich tails with length polymorphism. Detects and reports all the 7 alleles on the M Locus (Mh, M, Ma+, Ma, Mc+, Mc and m)

Mode of Inheritance:

Dominant with Variable Expressivity

OMIA Reference:

Click to View Full OMIA Reference

Fact Sheet:

Click to View Fact Sheet