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Hereditary Nasal Parakeratosis (Greyhound Type)

Description

Hereditary nasal parakeratosis (greyhound type) affects dogs and is an inherited skin disease.

Affected dogs (as puppies) will present with dry, rough, grey to brown crusts and rarely, painful cracks on the tip of the nose. The noses of affected dogs are prone to superficial bacterial infections and often become depigmented over time, however, affected dogs are otherwise healthy.

Symptoms often change and differ in severity over the dog’s life. Although this disease is manageable, it does require continuous topical therapy to prevent recurrence of excessive nasal crusting.

Recommended Breeding

Diseases

Hereditary Nasal Parakeratosis (Greyhound Type)

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Associated Breed(s):

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Labels:

Category:

Dermatologic - Associated with the skin

Severity:

Low-Moderate. This disease can cause some discomfort and/or dysfunction in the affected animal. It does not generally affect life expectancy.

Gene:

HNPK

Variant Detected:

chr2:21731812-21731815 (canFam3): 4 bp deletion (del AAGT)

Mode of Inheritance:

Autosomal Recessive

OMIA Reference:

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