home

Order Tests for Dogs

DNA Tests

Progressive Retinal Atrophy, Cone-Rod Dystrophy 3 (Glen of Imaal Terrier Type)

Description

Progressive Retinal Atrophy, Cone-Rod Dystrophy 3 (PRA-crd3) is an adult-onset inherited eye disease affecting Glen of Imaal Terriers.

PRA-crd3 occurs as a result of degeneration of both rod and cone type Photoreceptor Cells of the Retina, which are important for vision in dim and bright light.

Dogs affected with this disorder initially have changes in reflectivity and appearance of a structure behind the retina called the Tapetum that is typically observed on a veterinary eye exam at 3 years of age.

Between 3 and 5 years of age, affected dogs show signs of vision loss in dim light (night blindness) and loss of peripheral vision. Gradually visual deficits progress to complete vision loss over several years.

Recommended Breeding

Diseases

Progressive Retinal Atrophy, Cone-Rod Dystrophy 3 (Glen of Imaal Terrier Type)

$60.00

Associated Breed(s):

Click here to view Associated Breeds

Labels:

Category:

Ophthalmologic - Associated with the eyes and associated structures

Severity:

Low-Moderate. This disease can cause some discomfort and/or dysfunction in the affected animal. It does not generally affect life expectancy.

Gene:

ADAM9

Variant Detected:

chr16:26431182-26471957: 40 kb deletion

Mode of Inheritance:

Autosomal Recessive

OMIA Reference:

Click to View Full OMIA Reference